ALL SUBSTANCES INFORMATION SHEET FOR RGCC PROTOCOLS
Table of Contents
NATURAL SUBSTANCES INFORMATION
CLASS 1 CYTOTOXIC AGENTS
A cytotoxic agent is a substance that kills or damages cells, often by disrupting their division or vital functions.
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AGARICUS BLAZEI MURILL (Super Royal Agaricus/Emerson)
BENEFITS:
- Enhanced Immune Response: ABM contains polysaccharides, particularly beta-glucans, which have been shown to stimulate the immune system. This immune-boosting effect helps activate immune cells like macrophages, T-cells, and natural killer (NK) cells, which are essential for identifying and destroying cancer cells.
- Immunomodulatory Effects: ABM may regulate immune responses, helping to enhance the body's natural defenses against cancer growth and recurrence without overstimulating immune activity.
- Inhibition of Tumor Growth: Studies suggest that ABM can inhibit cancer cell proliferation and induce apoptosis (programmed cell death) in certain cancer cell lines.
- Reduction in Angiogenesis: ABM may inhibit angiogenesis, the process by which new blood vessels form to supply nutrients to tumors.
- Neutralization of Free Radicals: ABM is rich in antioxidants, which help reduce oxidative stress and protect cells from DNA damage.
- Potential to Improve Treatment Efficacy: ABM’s immune-boosting and antioxidant properties may complement conventional therapies, potentially enhancing their efficacy against cancer cells while protecting healthy cells.
- Reduction of Tumor-Promoting Inflammation: ABM’s anti-inflammatory effects can help reduce inflammation that might otherwise support tumor growth and spread, aiding in overall cancer management.
DOSING: 2 CAPS BID TAKEN ON EMPTY STOMACH
POSSIBLE SIDE EFFECTS:
- Nausea, Diarrhea, and Stomach Upset: Some individuals may experience mild gastrointestinal discomfort, such as nausea, diarrhea, or stomach upset, especially when first starting ABM or taking it in larger doses.
- Bloating and Gas: ABM can cause bloating or gas in some people, particularly those sensitive to high-fiber foods or mushrooms.
ARTECIN - (SWANSON)
Swanson Premium Full Spectrum Sweet Wormwood (Artemisia annua) 425 mg 90 Caps - Swanson®
Artecin is a dietary supplement containing an extract of Artemisia annua, commonly known as sweet wormwood or Chinese wormwood. Traditionally, Artemisia annua has been used to support gastrointestinal health by promoting a balanced intestinal microbiome and enhancing digestive enzyme and bile acid secretion. The active compound in this plant, artemisinin, is recognized for its antimalarial properties and is also being studied for potential applications in treating other parasitic infections and certain cancers.
BENEFITS:
- Mechanism of Action: Artemisinin and its derivatives work by generating free radicals that damage the malaria parasite's cellular structures, leading to its death. This mechanism targets the parasite's vulnerability within red blood cells.
- Potential Cancer Applications: Artemisinin is being researched for its potential anticancer effects, as studies suggest it may selectively target cancer cells, especially those high in iron, which cancer cells tend to accumulate. These findings, however, are still in the early stages and require further clinical studies.
- Other Potential Benefits: Some research suggests artemisinin may have anti-inflammatory, antiviral, and antimicrobial properties, but its primary use remains in malaria treatment.
DOSING: 2 CAPS BID- NO ARTECIN ON THE DAY OF EBOO*
POSSIBLE SIDE EFFECTS:
- Gastrointestinal Issues: Nausea, vomiting, stomach pain, and diarrhea are common side effects. These symptoms are generally mild but can be uncomfortable.
- Headache and Dizziness: Some users report headaches, dizziness, or feeling lightheaded, which may be due to the compound's effect on the central nervous system.
- Liver and Kidney Effects: Prolonged or high doses of artemisinin have been associated with liver and kidney stress in some cases. Regular monitoring is recommended for individuals on long-term therapy.
- Allergic Reactions: Although rare, some people may experience allergic reactions, such as rash, itching, or swelling.
- Blood Disorders: In rare cases, artemisinin compounds can affect red blood cells, potentially leading to hemolytic anemia or other blood disorders, particularly in individuals with certain genetic conditions (e.g., G6PD deficiency).
ARTEMISININ (ALLERGY RESEARCH/EMERSON) (200MG)
BENEFITS:
Artemisinin is a compound derived from the Artemisia annua plant, also known as sweet wormwood or Qinghao in traditional Chinese medicine. It is widely known for its antimalarial properties and is a core treatment for malaria, especially in artemisinin-based combination therapies (ACTs), which are highly effective against Plasmodium falciparum, the parasite responsible for severe malaria.
- Mechanism of Action: Artemisinin and its derivatives work by generating free radicals that damage the malaria parasite's cellular structures, leading to its death. This mechanism targets the parasite's vulnerability within red blood cells.
- Potential Cancer Applications: Artemisinin is being researched for its potential anticancer effects, as studies suggest it may selectively target cancer cells, especially those high in iron, which cancer cells tend to accumulate. These findings, however, are still in the early stages and require further clinical studies.
- Other Potential Benefits: Some research suggests artemisinin may have anti-inflammatory, antiviral, and antimicrobial properties, but its primary use remains in malaria treatment.
DOSING: 2 CAP BID- TAKE OFF WEEKENDS- TAKE WITH FATTY FOOD |NO ARTEMISININ ON DAY OF EBOO
POSSIBLE SIDE EFFECTS
- Gastrointestinal Issues: Nausea, vomiting, stomach pain, and diarrhea are common side effects. These symptoms are generally mild but can be uncomfortable.
- Headache and Dizziness: Some users report headaches, dizziness, or feeling lightheaded, which may be due to the compound's effect on the central nervous system.
- Liver and Kidney Effects: Prolonged or high doses of artemisinin have been associated with liver and kidney stress in some cases. Regular monitoring is recommended for individuals on long-term therapy.
- Allergic Reactions: Although rare, some people may experience allergic reactions, such as rash, itching, or swelling.
- Blood Disorders: In rare cases, artemisinin compounds can affect red blood cells, potentially leading to hemolytic anemia or other blood disorders, particularly in individuals with certain genetic conditions (e.g., G6PD deficiency).
ASCORBIC ACID (DAVINICI LABS/EMERSON)
Immune Boost: Vitamin C supports the immune system, which is critical in helping the body recognize and fight cancer cells. It aids in the production and function of immune cells, like neutrophils, lymphocytes, and phagocytes, which are essential for targeting and destroying cancer cells.
BENEFITS:
- Reduction of Oxidative Stress: As an antioxidant, vitamin C can help neutralize free radicals, reducing oxidative damage to cells and DNA. This is particularly important in cancer, where oxidative stress plays a role in promoting tumor growth.
- Cytotoxic Effects on Cancer Cells: When given at very high doses intravenously, vitamin C can act as a pro-oxidant rather than an antioxidant. This process generates hydrogen peroxide in the body, which can be toxic to cancer cells while sparing normal cells. This effect is thought to be especially beneficial for killing cancer cells in cases of aggressive or treatment-resistant cancers.
- Potential Synergy with Chemotherapy and Radiation: High-dose vitamin C has been explored as an adjunct to chemotherapy and radiation, where it may improve the effectiveness of these treatments by enhancing oxidative stress in cancer cells. This can make cancer cells more susceptible to treatment and potentially reduce required doses of chemotherapy drugs, thereby limiting side effects.
- Limiting Tumor Spread: By supporting healthy tissue structure through collagen synthesis, vitamin C may help contain tumor growth and limit the spread of cancer cells. Research indicates that vitamin C may help slow the process of metastasis by stabilizing the extracellular matrix around cells.
- Influencing Cancer Cell Metabolism: Some cancer cells have altered metabolism that makes them vulnerable to high levels of vitamin C. In laboratory studies, high doses of vitamin C have been shown to interfere with cancer cell energy production, potentially limiting their growth.
- DNA Repair and Protection: As an antioxidant, vitamin C helps protect cells from DNA mutations that can lead to cancer or exacerbate existing cancers. This protective effect may help slow the progression of precancerous cells and reduce the likelihood of cancer cell mutations.
DOSING: 5GM BID- NO ORAL VIT C AND ECGC ON THE DAY OF IV
POSSIBLE SIDE EFFECT:
- Nausea and Vomiting: High doses of vitamin C, especially when taken orally, can irritate the digestive system, causing nausea or vomiting.
- Diarrhea: Vitamin C has an osmotic effect, which can draw water into the intestines, leading to loose stools or diarrhea, particularly at doses over 2,000 mg.
- Abdominal Cramps and Bloating: Some people may experience cramping, bloating, or gas as a result of excess vitamin C intake.
- Increased Risk of Oxalate Stones: High doses of vitamin C can increase levels of oxalate, a byproduct of vitamin C metabolism, which may lead to kidney stone formation, particularly in those predisposed to oxalate kidney stones.
- Vitamin C enhances iron absorption, which can be beneficial for those with low iron levels but may be problematic for individuals with hemochromatosis (a condition causing excessive iron accumulation).
- High doses of vitamin C can interfere with certain lab tests, leading to falsely elevated or decreased blood glucose readings
- Anticoagulant Interaction: Vitamin C can interfere with the efficacy of anticoagulant medications like warfarin, so those on blood thinners should consult their healthcare provider before taking high doses.
- Some people undergoing high-dose intravenous vitamin C therapy report mild headaches or fatigue, which generally subside after the infusion.
AVEMAR PULVIS (AVEMAR)
https://www.avemar.co/avemar-pulvis/
BENEFITS:
Avemar Pulvis is a fermented wheat germ extract developed to support cancer treatment and immune system modulation. Its potential benefits include:
- Immune System Support: Avemar Pulvis may enhance the body's natural defenses by modulating immune responses, improving the identification and elimination of abnormal cells.
- Antioxidant Properties: The extract contains compounds that reduce oxidative stress, which is associated with various chronic diseases, including cancer.
- Support for Cellular Metabolism: Regulate cellular metabolism, inhibiting the proliferation of malignant cells.
DOSING:
- Adults weighing up to 90 kg (198 lbs): Take one packet (17 g) daily.
- Adults weighing over 90 kg (198 lbs): Take two packets daily, one in the morning and one in the evening.
To prepare, dissolve the contents of one packet in 100-200 ml of water or a non-hot beverage, and consume immediately
POSSIBLE SIDE EFFECTS:
Avemar Pulvis has been used in Hungary since 1998 and is approved in several countries as a "medical nutriment for cancer patients." Acute and subacute toxicity studies in rodents administered Avemar Pulvis at doses significantly exceeding the normal recommended dosage showed no adverse effects.
- Gastrointestinal Issues: Nausea, vomiting, diarrhea, or constipation.
- Allergic Reactions: Rash, itching, or swelling, particularly in those with wheat allergies.
- Blood Sugar Changes: Potential alterations in blood glucose levels, may affect individuals with diabetes.
BLACK CUMIN: (LIFE EXTENSION/EMERSON)
Black cumin (Nigella sativa), aka-black seed has the bioactive compound primarily thymoquinone.
BENEFITS:
- Reduction of Oxidative Stress: Thymoquinone acts as a powerful antioxidant, reducing oxidative stress and DNA damage that can contribute to cancer development. By scavenging free radicals, black cumin helps protect cells from mutations.
- Lowering Inflammation: Chronic inflammation is linked to cancer progression. Thymoquinone has anti-inflammatory properties that help suppress inflammatory pathways involved in cancer, slowing tumor growth.
- Induction of Apoptosis: Thymoquinone has been shown to induce apoptosis (programmed cell death) in various cancer cell lines, including those for breast, lung, colon, and prostate cancers. This process selectively targets cancer cells while sparing healthy cells.
- Inhibition of Cell Proliferation: Studies suggest that black cumin extracts inhibit the rapid division of cancer cells, thus slowing tumor growth.
- Modulation of Immune Response: Black cumin may enhance immune system function, helping the body recognize and attack cancer cells more effectively.
- Enhancement of Chemotherapy and Radiation Effects: Black cumin may improve the efficacy of conventional treatments like chemotherapy and radiation by making cancer cells more susceptible to these therapies. Additionally, it may reduce the side effects associated with these treatments.
- Inhibition of Cancer Spread: Thymoquinone has been observed to suppress angiogenesis (the formation of new blood vessels) and metastasis, which are critical for the spread of cancer to other parts of the body.
DOSING: 2 CAPS BID
POSSIBLE SIDE EFFECTS:
- Nausea and Bloating: Some individuals report mild nausea, bloating, or digestive discomfort, particularly when taking black cumin oil on an empty stomach.
- Stomach Upset: High doses may irritate the stomach lining, leading to upset stomach or cramps.
- Hypoglycemia: Black cumin can lower blood sugar levels, which may lead to hypoglycemia (low blood sugar) in people with diabetes, especially if they are taking blood sugar-lowering medications.
- Lowered Blood Pressure: Black cumin may lower blood pressure, which can be beneficial for some but may cause hypotension (low blood pressure) in people taking blood pressure medications.
- Blood-Thinning Effects: Black cumin has mild anticoagulant properties, which could increase bleeding risk if taken with blood-thinning medications (e.g., warfarin, and aspirin).
BUTYRIC ACID (BODYBIO) (SODIUM BUTYRATE) (1.2GM)
BENEFITS:
- Promoting Programmed Cell Death: Butyric acid has been observed to induce apoptosis (programmed cell death) in certain cancer cells, especially in colorectal cancer. This can help reduce tumor size and slow cancer progression.
- Anti-Proliferative Effects: Butyric acid can inhibit the rapid division of cancer cells by influencing gene expression and slowing cell cycle progression. This helps prevent the uncontrolled growth typical of cancer cells.
- Reducing Chronic Inflammation: Chronic inflammation is linked to cancer development, particularly in the gastrointestinal tract. Butyric acid has anti-inflammatory properties that may reduce the inflammatory signals that contribute to cancer progression.
- Support for a Healthy Gut: Butyric acid nourishes colon cells, maintaining gut integrity and preventing harmful bacteria and toxins from triggering inflammation or promoting cancerous changes in the gut lining. This is particularly beneficial for colorectal health.
- Regulation of Gene Expression: Butyric acid is a known inhibitor of histone deacetylases (HDACs), enzymes that affect gene expression. By inhibiting HDACs, butyric acid can activate tumor-suppressor genes and silence oncogenes, reducing
DOSING: 2 CAPS BID
POSSIBLE SIDE EFFECTS:
- Nausea, Bloating, and Gas: Some individuals experience mild nausea, bloating, or gas when taking butyric acid supplements, particularly if taken in large amounts.
- Diarrhea or Loose Stools: Butyric acid can increase intestinal motility, potentially leading to diarrhea or more frequent bowel movements in sensitive individuals.
- Unpleasant Odor: Butyric acid has a strong, rancid smell, which can sometimes result in a temporary body odor or bad breath after taking the supplement.
- Mild Headache: In rare cases, some people may experience a mild headache or general fatigue when starting butyric acid supplements, possibly due to adjustments in gut microbiota or metabolic changes.
COLLOIDAL SILVER (ARGENTYN 23/EMERSON)
BENEFITS:
- Preventing Infections: Cancer patients often have compromised immune systems, making them more susceptible to infections. Colloidal silver has broad-spectrum antimicrobial effects, which may help prevent or manage infections by reducing exposure to bacteria, viruses, and fungi.
- Immunomodulation: Stimulates the immune system, enabling it to more effectively identify and attack cancer cells.
- Cytotoxic Effects on Cancer Cells: Cytotoxic effects on certain cancer cell lines in the lab (in vitro), suggest potential for directly inhibiting cancer cell growth.
- Reducing Inflammation: Mild anti-inflammatory properties, which could help reduce chronic inflammation associated with cancer progression.
DOSING: 15ML TID
POSSIBLE SIDE EFFECTS:
- Blue-Gray Skin Tone: The most well-known side effect is argyria, a condition in which silver particles accumulate in the body, causing a permanent blue-gray discoloration of the skin and mucous membranes. This is irreversible and can occur with long-term use or high doses.
- Organ Toxicity: Excessive silver intake can lead to kidney and liver damage as these organs work to filter out the silver particles.
- Potential Neurological Issues: In some cases, silver accumulation has been associated with neurological symptoms, such as seizures, tremors, or muscle weakness, particularly with prolonged or high-dose use.
- Nausea and Gastric Irritation: Colloidal silver can cause gastrointestinal discomfort, including nausea, stomach upset, and even diarrhea, especially when taken in high doses.
- Reduced Medication Effectiveness: Colloidal silver may interact with certain medications, including antibiotics and thyroid medications, reducing their effectiveness
COQNOL 200 (DFH)
BENEFITS:
- Improving Energy Levels: CoQ10 is essential for mitochondrial function, where it helps produce ATP (energy) in cells. Cancer and its treatments can cause fatigue and reduced energy production, so supplementing with CoQ10 may help boost energy levels, especially in fatigued patients.
- Reducing Oxidative Stress: CoQ10 is a powerful antioxidant that helps neutralize free radicals and reduces oxidative damage to cells. This protective effect may be particularly beneficial during chemotherapy and radiation, as these treatments
- Protecting Against Cardiotoxicity: Some cancer treatments, particularly certain chemotherapy drugs (like anthracyclines), can cause heart damage. CoQ10 has been studied for its ability to support heart health and may help reduce cardiotoxicity, preserving heart function during and after treatment.
- Enhancing Immune Response: CoQ10 has been associated with improved immune function, potentially enhancing the body’s natural defenses against cancer cell growth and progression. A strong immune system is essential for fighting off infections and managing cancer-related symptoms.
Slowing Tumor Growth: Some studies have suggested that CoQ10 may inhibit cancer cell growth and metastasis by regulating gene expression and cellular signaling pathways. However, these findings are preliminary, and more research is needed to confirm CoQ10's direct effects on cancer cells.
DOSING:1 CAP PO BID
POSSIBLE SIDE EFFECTS:
- Nausea, Stomach Upset, and Diarrhea: Some people report mild digestive discomfort, including nausea, stomach upset, or diarrhea, particularly when starting CoQnol or taking it on an empty stomach
- Increased Alertness: CoQnol may cause mild insomnia or difficulty sleeping if taken too late in the day, as CoQ10 plays a role in cellular energy production, which could lead to increased alertness.
- Mild Headaches: Some individuals may experience headaches or dizziness, particularly at higher doses or when starting supplementation.
- Hypotension: CoQnol can lower blood pressure, which can be beneficial for those with hypertension but may lead to hypotension (low blood pressure) in others. This is especially relevant for individuals already taking blood pressure medications.
- Reduced Effectiveness of Warfarin: CoQnol can interact with blood-thinning medications like warfarin, potentially reducing their effectiveness. Those taking blood thinners should consult their healthcare provider before using CoQnol.
CORDYCEPS 600 MG (SWANSON)
ansonvitamins.com/p/swanson-premium-cordyceps-600-mg-120-caps
C-STATIN (AIDAN PRODUCTS/EMERSON)
BENEFITS:
- C-StatinTM capsules are an all-natural nutritional supplement proven to support normal angiogenesis.
- C-StatinTM contains a proprietary extract of bindweed, comprised of proteoglycan molecules (PGMs) and has no recorded adverse side effects. It does contain shark cartilage. PGMs have been demonstrated to have significant anti-angiogenic and immunostimulatory effects.
- C-StatinTM has been shown to inhibit new blood vessel growth up to 73% and abnormal cell growth up to 96.8%.
DOSING: 3 CAP BID
POSSIBLE SIDE EFFECTS:
- Nausea, vomiting, diarrhea, or constipation.
- Individuals with seafood allergies, particularly to shark products, may experience allergic reactions, including rash, itching, or swelling.
- Shark cartilage supplements have been associated with elevated calcium levels in the blood, leading to symptoms such as fatigue, nausea, and confusion.
- A metallic or unpleasant taste has been reported by some users.
- Interaction with certain medications, including anticoagulants and immunosuppressants, potentially altering their effectiveness
DCA (DCALABS.COM)
BENEFITS:
- Metabolic Modulation: DCA is believed to shift cancer cell metabolism from glycolysis (sugar fermentation) to glucose oxidation, potentially inhibiting cancer cell growth.
- Induction of Apoptosis: By altering mitochondrial function, DCA may promote programmed cell death in cancer cells, reducing tumor proliferation.
- Selective Targeting: DCA is thought to preferentially affect cancer cells while sparing normal cells, potentially minimizing damage to healthy tissues.
DOSING: 10-12.5 mg/kg of body weight per day - MUST CHECK LFT’S AFTER 4 WEEKS
POSSIBLE SIDE EFFECTS:
- Peripheral Neuropathy: DCA is known to cause peripheral neuropathy (nerve damage), resulting in symptoms like tingling, numbness, and a "pins and needles" sensation in the hands and feet. This is one of the most common side effects and may be reversible if caught early and dosing is adjusted.
- Nausea, Vomiting, and Stomach Pain: Some users experience gastrointestinal discomfort, especially when starting DCA or at higher doses. Diarrhea and loss of appetite may also occur.
- Elevated Liver Enzymes: DCA has been associated with liver toxicity in some cases, leading to increased liver enzymes. Monitoring liver function is essential during DCA use, as prolonged exposure may cause liver strain or damage.
- Tiredness and Muscle Weakness: Some patients report fatigue and muscle weakness, which may affect physical endurance and daily functioning.
- Mood Changes and Cognitive Impairment: DCA may cause mood swings, memory issues, or cognitive difficulties in some individuals. This is less common but should be noted, especially with prolonged use.
- Headaches and Dizziness: Some users report headaches and a sense of dizziness or unsteadiness.
- Electrolyte Imbalance: DCA can lead to low potassium levels, which can cause symptoms like muscle cramps, fatigue, and irregular heart rhythms. Monitoring electrolyte levels is advised during DCA use.
DOXYCYCLINE (COMMERCIAL OR CMP)
BENEFITS:
- Targeting Cancer Stem Cells: InhibitS mitochondrial function in cancer stem cells, which play a key role in cancer progression, resistance to treatment, and recurrence.
- Reducing Blood Supply to Tumors: Anti-angiogenic properties, meaning it can inhibit the formation of new blood vessels that supply tumors with nutrients.
- Impacting Cancer Cell Surroundings: Alter the tumor microenvironment, making it less hospitable for cancer growth. It has been shown to reduce the activity of matrix metalloproteinases (MMPs), enzymes that cancer cells use to degrade surrounding tissue and invade other parts of the body.
- Reducing Tumor-Associated Inflammation: Anti-inflammatory effects, which may help reduce chronic inflammation associated with cancer progression.
- Interfering with Cancer Cell Metabolism: Inhibit mitochondrial function, forcing cancer cells to rely on less efficient metabolic pathways.
DOSING: 100mg oral capsule: 1 CAP BID
POSSIBLE SIDE EFFECTS:
- Nausea, Vomiting, and Diarrhea: Doxycycline can irritate the gastrointestinal tract, causing nausea, vomiting, or diarrhea, especially when taken on an empty stomach.
- Esophagitis and Ulcers: Doxycycline can cause irritation or ulcers in the esophagus. Taking it with a full glass of water and avoiding lying down for at least 30 minutes after taking it can reduce this risk.
- Increased Sun Sensitivity: Doxycycline can make the skin more sensitive to sunlight, increasing the risk of sunburn. It's advised to use sunscreen and protective clothing when outdoors.
- ALLERGIC REACTION: Rash, Hives, and Swelling: Some people may experience allergic reactions to doxycycline, ranging from mild rashes to more severe swelling or difficulty breathing (anaphylaxis).
- Potential Liver Strain: Long-term use or high doses may put strain on the liver, particularly in individuals with pre-existing liver conditions.
- Kidney Effects: Doxycycline is generally safe for the kidneys, but individuals with kidney disease should still use it cautiously, as it can affect kidney function in rare cases.
- Potential for Hypoglycemia: There have been rare reports of doxycycline affecting blood sugar levels, especially in individuals with diabetes.
- Headache and Blurred Vision: Doxycycline may occasionally cause intracranial hypertension, which can lead to headaches, blurred vision, and, in rare cases, more severe neurological symptoms.
- Risk of Fungal Infections: Because doxycycline can disrupt the balance of bacteria in the body, it may increase the risk of yeast infections, particularly in women.
FRANKINCENSE (BOSWELLIA PHYTOSOME/EMERSON)
BENEFITS:
- Reduction of Tumor-Related Inflammation: Boswellia’s active compounds, particularly boswellic acids, inhibit the 5-lipoxygenase enzyme, which plays a role in the inflammatory process.
- Apoptosis Induction: Some studies suggest that boswellic acids may induce apoptosis (programmed cell death) in various cancer cell lines, including brain, prostate, and colon cancers.
- Inhibition of Tumor Angiogenesis: Boswellia may also inhibit the formation of new blood vessels that tumors need for growth and spread (angiogenesis).
- Immune Modulation: Boswellia may support immune system function, helping the body recognize and target cancer cells.
- Low Toxicity Profile: Boswellia is generally well-tolerated and has a low toxicity profile, making it a safe option as a complementary therapy. Its phytosome formulation improves absorption, which can enhance its effectiveness while minimizing the dosage required.
DOSING (350MG): 1 CAP IN AM AND 2 CAPS IN PM
POSSIBLE SIDE EFFECTS:
- Stomach Upset: Some people may experience mild stomach discomfort, including nausea, stomach pain, and indigestion.
- Diarrhea or Constipation: Digestive disturbances like diarrhea or constipation may occur in sensitive individuals.
INOSITOL (DFH)
BENEFITS:
- Inhibition of Cancer Cell Growth: Inositol, particularly in the form of inositol hexaphosphate (IP6), has been studied for its ability to inhibit cell proliferation in various types of cancer, including breast, prostate, and colon cancers. It can help slow down abnormal cell growth by regulating cell cycle processes.
- Promotion of Apoptosis: Inositol may help induce apoptosis (programmed cell death) in cancer cells, which is essential for controlling tumor size and preventing cancer progression.
- Enhancing Immune Function: Inositol and IP6 may modulate immune response by stimulating the activity of natural killer (NK) cells and T-cells, which are critical for identifying and destroying cancer cells. This can support the body’s natural defenses against cancer growth and spread.
- Reducing Tumor Blood Supply: Inositol has shown anti-angiogenic effects, meaning it may help inhibit the formation of new blood vessels that supply tumors with nutrients and oxygen. This can slow down tumor growth and reduce the potential for metastasis.
- Reduction of Oxidative Stress: Inositol acts as an antioxidant, helping to protect cells from oxidative damage. This is particularly valuable in cancer care, as oxidative stress contributes to DNA mutations, tumor growth, and treatment side effects.
- Reduction in Metastasis Potential: Studies suggest that inositol, especially in combination with IP6, may reduce the potential for metastasis and cancer recurrence by inhibiting cancer cell adhesion, invasion, and migration.
DOSING 900MG: 1 CAP IN AM AND 2 CAPS IN PM
POSSIBLE SIDE EFFECTS:
- Nausea and Stomach Discomfort: Some individuals may experience mild nausea, bloating, or stomach discomfort, especially when starting inositol or taking it in high doses.
- Diarrhea: Higher doses of inositol can sometimes lead to loose stools or diarrhea.
- Mild Headaches: Some users report mild headaches or dizziness, particularly if taking inositol for the first time or using higher doses. These symptoms are usually temporary.
- Hypoglycemia Risk: Inositol can influence blood sugar levels, which may cause hypoglycemia (low blood sugar) in individuals sensitive to blood sugar changes, especially those on glucose-lowering medications.
- Feeling Tired: Inositol may cause mild drowsiness or fatigue in some people, particularly in higher doses, as it can have a calming effect.
- Interaction with Mood Stabilizers: Inositol has mood-modulating effects, so it may interact with certain medications, particularly mood stabilizers or antidepressants.
LYCOPENE (PUR ENCAPSULATIONS/EMERSON)
Lycopene, a powerful antioxidant found in red and pink fruits like tomatoes, watermelon, and pink grapefruit, has been studied for its potential protective effects against certain types of cancer
**Absorption: Lycopene is fat-soluble, so it is best absorbed when consumed with healthy fats (like olive oil).
BENEFITS:
- Reduction of Oxidative Stress: Neutralizes free radicals, reducing oxidative damage to cells and DNA, which is crucial in preventing mutations that can lead to cancer. Its antioxidant activity may help protect healthy cells from oxidative stress, particularly in tissues where lycopene accumulates, such as the prostate, lungs, and skin.
- Prevention of Cell Proliferation: Slow the growth of cancer cells by regulating cell cycle progression, which can limit tumor expansion.
- Reducing Tumor-Promoting Inflammation: Chronic inflammation can contribute to cancer development and progression. Lycopene has anti-inflammatory properties that may lower inflammatory signals within the body, reducing the risk of cancer and potentially inhibiting tumor growth in certain cancers, such as prostate and colon cancer.
- Prostate Health: Lycopene is particularly concentrated in the prostate and has shown promising results in reducing prostate cancer risk and progression. Research indicates that lycopene may help reduce levels of prostate-specific antigen (PSA) and slow the progression of early-stage prostate cancer.
- Promotion of Cancer Cell Death: Induce apoptosis (programmed cell death) in cancer cells, an essential mechanism for stopping tumor growth. This effect has been observed in studies on various cancer types, including breast, lung, and liver cancer.
- Prevention of Cancer Spread: Reduce the expression of enzymes that cancer cells use to invade surrounding tissues. By limiting these enzymes, lycopene can inhibit metastasis, particularly in cancers like breast and gastric cancer.
- Skin Cancer Prevention: Protect the skin against damage from UV radiation, which is a significant factor in skin cancer development. It has been shown to reduce skin cell damage and inflammation after UV exposure, potentially lowering skin cancer risk.
DOSING 20MG: 2 CAPS BID WITH FOOD
POSSIBLE SIDE EFFECTS:
- Nausea, Vomiting, and Diarrhea: High doses of lycopene supplements may cause digestive discomfort, including nausea, vomiting, and diarrhea.
- Bloating and Gas: Some people report bloating and gas, particularly with high-dose supplements.
- Orange Discoloration: Excessive lycopene intake can cause a harmless condition called lycopenodermia, where the skin takes on an orange or reddish tint, particularly on the palms and soles. This effect usually resolves when lycopene intake is reduced.
- Potential Blood Pressure Lowering Effect: Lycopene may have a mild blood pressure-lowering effect, which can be beneficial for those with high blood pressure but may lead to hypotension in people with already low blood pressure.
- Blood Pressure and Antiplatelet Medications: Lycopene may interact with blood pressure medications and antiplatelet drugs, potentially amplifying their effects. People on these medications should consult a healthcare provider before taking lycopene supplements.
MODIFIED CITRUS PECTIN (ALLERGY RESEARCH GROUP/EMERSON)
DOSING 1.5GM: 3 CAPS BID
ONKOBEL PRO (BELJANSKI)(MUST BE ORDERED BY PROVIDER)
https://www.maisonbeljanski.com/products/onkobel-pro
OnKobel-Pro® is a dietary supplement formulated to support cellular health, particularly in the context of cancer care. It combines three plant extracts: Pao pereira, Rauwolfia vomitoria, and golden leaf Ginkgo biloba
BENEFITS:
- Inhibition of Cancer Cell Growth: Pao pereira extract has been studied for its potential to suppress the proliferation of cancer cells, including prostate and pancreatic cancers. It may induce apoptosis (programmed cell death) in malignant cells, thereby inhibiting tumor growth.
- Anti-Inflammatory Effects: This extract may exert significant anti-inflammatory effects, supporting the immune system and potentially reducing inflammation associated with cancer progression.
- Selective Targeting of Abnormal Cells: Rauwolfia vomitoria extract is believed to selectively target destabilized DNA in abnormal cells, promoting their elimination while sparing healthy cells.
- Hormonal Balance: This extract may help normalize hormone levels in both male and female reproductive systems, which can be beneficial in hormone-sensitive cancers.
- Antioxidant Properties: The golden leaves of Ginkgo biloba are rich in antioxidants, offering protective effects on tissues exposed to various forms of electromagnetic radiation, such as during radiation therapy.
- Enzyme Regulation: This extract may help regulate ribonuclease enzymes that can become deregulated under cellular stress, maintaining homeostasis and supporting healthy cellular function.
DOSING: 3 CAPS BID AWAY FROM FOOD*
POSSIBLE SIDE EFFECTS:
- Stomach upset
- Headache
- Dizziness
- Allergic skin reactions
OXALOACETATE (BENAGENE) (Full Scripts)
https://us.fullscript.com/o/wholesale/products/U3ByZWU6OlByb2R1Y3QtOTEzOTY=
BENEFITS:
- Caloric Restriction Mimetic: Oxaloacetate has been studied for its ability to mimic the effects of caloric restriction, a dietary approach associated with extended lifespan and reduced cancer incidence. By influencing metabolic pathways, oxaloacetate may help create an internal environment less conducive to cancer cell proliferation.
- Protection Against Glutamate Toxicity: Elevated glutamate levels can contribute to neurotoxicity, which is a concern in certain cancers, such as gliomas. Oxaloacetate has been shown to reduce blood glutamate levels, potentially offering neuroprotection.
- Enhancement of Cellular Energy: By participating in the Krebs cycle, oxaloacetate supports mitochondrial function and energy production.
DOSING: 2 CAPS BID
POSSIBLE SIDE EFFECTS:
- Nausea, Stomach Upset, and Diarrhea: Some individuals report mild digestive discomfort, including nausea or diarrhea, particularly when starting benaGene® or taking it in larger doses.
- Mild Headache: A few users have experienced headaches, likely due to metabolic changes or alterations in blood sugar levels.
- Potential Impact on Blood Glucose: Oxaloacetate can influence blood sugar levels, which may cause mild hypoglycemia (low blood sugar) in sensitive individuals, particularly those on glucose-lowering medications.
- Feelings of Fatigue: Some users report feeling tired or drowsy, especially during the initial phase of supplementation.
PAU D’ARCO (DR MERCOLA/EMERSON)
BENEFITS:
- Reduction of Oxidative Stress: Pau d'Arco contains antioxidants that help neutralize free radicals, reducing oxidative stress and DNA damage. Reduction of Tumor-Promoting Inflammation: Pau d'Arco’s anti-inflammatory properties may help decrease the inflammatory signals associated with tumor growth, potentially slowing cancer cell proliferation.
- Inhibition of Cancer Cell Growth: Compounds in Pau d'Arco, such as lapachol and beta-apache, have been shown to inhibit the growth of cancer cells in laboratory studies. These compounds may disrupt cancer cell metabolism and prevent cancer cells from multiplying.
- Induction of Apoptosis: Promote apoptosis (programmed cell death) in cancer cells, an important mechanism for limiting tumor growth and supporting healthy cell turnover.
- Enhancement of Immune Function: Stimulate immune activity, helping the body recognize and target abnormal cells.
- Supporting a Balanced Microbiome: Natural antimicrobial properties, which may help maintain a healthy balance of bacteria and other microbes.
DOSING 1GM: 2 CAPS BID
POSSIBLE SIDE EFFECTS:
- Nausea, Vomiting, and Diarrhea: Some people may experience nausea, vomiting, or diarrhea, especially when taking higher doses.
- Dizziness and Lightheadedness: Pau d'Arco can cause dizziness or lightheadedness in some users, particularly at higher doses.
- Headaches: Occasional mild headaches have been reported, possibly due to the body's adjustment to the supplement.
- Anticoagulant Effects: Pau d'Arco may have mild blood-thinning effects, increasing the risk of bleeding. Individuals taking anticoagulant medications or those with bleeding disorders should use it cautiously.
PANCREATIN 10X ULTRA
https://us.fullscript.com/o/wholesale/products/U3ByZWU6OlByb2R1Y3QtODg3NDQ=
POLY-MVA (POLY MVA/AMAZON)
Poly-MVA is a dietary supplement that contains a blend of lipoic acid, palladium, vitamins (B1, B2, B12), amino acids, and other nutrients. It’s primarily used as a supportive therapy in cancer care, with a focus on enhancing cellular health, energy production, and immune function
BENEFITS:
- Enhanced Mitochondrial Function: Poly-MVA contains lipoic acid and palladium, which together may support mitochondrial health and cellular energy production.
- Reduction of Oxidative Stress: Antioxidant properties that may protect healthy cells from oxidative damage caused by free radicals, which is especially important during chemotherapy or radiation therapy.
- Protection of DNA Integrity: By providing nutrients that support DNA repair mechanisms, Poly-MVA may help maintain cellular health and prevent further mutations, which is particularly valuable in cancer prevention and slowing progression.
- Immune Modulation: The ingredients in Poly-MVA, including B vitamins and amino acids, support immune function by enhancing the production and activity of immune cells.
- Reduction of Tumor-Related Inflammation: Chronic inflammation can contribute to cancer progression. Poly-MVA contains ingredients with mild anti-inflammatory properties, which may help reduce inflammation, support healthy cell signaling, and slow tumor growth.
DOSING: Do not take within 6 hours of IV vitamin C. Do not use it at night. Use on an empty stomach which is at least 30 minutes before food. It does not taste great so can be followed with a drink of choice. The company recommends a CoQ10 be taken with each dose of this supplement. Day one: Start with 1 tsp, Day two: Increase to 2 tsp, Day three: Increase to 4 tsp, Day four: Increase to 8 tsp (broken into at least two doses, ideal is 2 tsp four times daily
POSSIBLE SIDE EFFECTS:
- Nausea, Stomach Upset, and Diarrhea: Some individuals may experience mild digestive discomfort, such as nausea or diarrhea, particularly when first starting Poly-MVA or taking it in larger amounts.
- Metallic Taste: Due to its palladium content, some people report a metallic taste when taking Poly-MVA, which can be temporary.
- Feeling Tired: Some users have reported mild fatigue or drowsiness, possibly due to detoxification effects or the body adjusting to the supplement.
- Headache: Some users may experience mild headaches or dizziness, especially if taking higher doses. This is generally temporary and can often be mitigated by adjusting the dose.
SALICINIUM: (PERFECT BALANCE)- NOT WELL TOLERATED- DO NOT USE
VITAMIN D- MUST USE THIS SPECIFIC VITAMIN D AS THIS IS THE ONE THAT WAS TESTED BY RGCC
DOSING: 5,000 IU TWICE DAILY (vs once daily) to keep levels in steady state
SIDE EFFECTS:
Hypercalcemia (High Blood Calcium Levels)- Symptoms: Nausea, vomiting, loss of appetite, excessive thirst, frequent urination, abdominal pain, and confusion. This is the most serious side effect of excessive vitamin D, as it increases calcium absorption from the gut and can lead to dangerously high calcium levels.
Kidney Issues- High calcium levels can lead to kidney stones and may strain the kidneys, potentially leading to kidney damage if excessive vitamin D intake continues. In extreme cases, hypercalcemia can cause renal (kidney) failure.
Gastrointestinal Symptom- High doses of vitamin D can cause nausea, vomiting, constipation, or diarrhea. Some people may also experience abdominal pain or cramps.
Bone Pain and Weakness- Excessive vitamin D intake over time can paradoxically weaken bones because high blood calcium levels can lead to reduced bone mineralization.
Mental and Mood Changes- High levels of calcium due to vitamin D toxicity can cause confusion, depression, and in severe cases, psychosis.
Fatigue and Weakness- People with high levels of vitamin D may feel tired or weak due to the impact of excess calcium on muscle function.
- Increased Risk of Heart Problems- Prolonged high calcium levels can lead to calcification of blood vessels and other tissues, which may increase the risk of heart disease over time.
VITANOX (STANDARD PROCESS)
https://www.standardprocess.com/
BENEFITS:
- Antioxidant Activity: Rosemary contains phenolic diterpenes, such as carnosol and rosmarinic acid, which help neutralize free radicals, thereby protecting cells from oxidative stress.
- Anti-Inflammatory Effects: These compounds may also reduce inflammation, a factor associated with various chronic diseases.
- Polyphenols and Catechins: Rich in epigallocatechin gallate (EGCG), green tea extract exhibits strong antioxidant properties, supporting cellular health.
- Potential Anti-Cancer Properties: Some studies suggest that green tea polyphenols may inhibit cancer cell proliferation and induce apoptosis, though more research is needed to confirm these effects.
- Curcuminoids: Turmeric contains curcumin, known for its anti-inflammatory and antioxidant activities, which may contribute to cellular protection.
Support for Healthy Liver Function: Curcumin has been studied for its role in supporting liver health and detoxification processes. - Oligomeric Procyanidins: These compounds provide antioxidant activity, supporting healthy circulation and vascular integrity.
- Maintenance of Healthy Connective Tissue: Grape seed extract may help maintain healthy connective tissue, contributing to overall cellular health.
DOSING: 1 CAP BID
POSSIBLE SIDE EFFECTS:
- Nausea, Upset Stomach, and Diarrhea: Some users may experience digestive discomfort, including nausea, stomach upset, or diarrhea, especially when starting Vitanox® or taking it in larger doses.
- Heartburn: Turmeric and green tea extract can sometimes cause heartburn or acid reflux in sensitive individuals.
- Green Tea Extract Concerns: High doses of green tea extract have, in rare cases, been associated with liver toxicity. Although uncommon, monitoring liver function is recommended if taking green tea supplements for extended periods.
- Mild Blood-Thinning: Grape seed extract and green tea may have mild anticoagulant effects, which can increase bleeding risk, particularly for those on blood-thinning medications.
- Potential Blood Pressure Lowering: Vitanox® may cause mild drops in blood pressure, which could affect those with low blood pressure or those on blood pressure-lowering medications.
Potential Reduction in Iron Absorption: Certain polyphenols in green tea can inhibit iron absorption from food.
CLASS 2- IMMUNOMODULATORS
FUCOIDAN (FUCOIDANFORCE)
https://fucoidanforce.com/fucoidan-force-dosage/
BENEFITS:
- Promoting Cancer Cell Death: Fucoidan has been shown to induce apoptosis (programmed cell death) in various cancer cell lines, including those for breast, liver, colon, and lung cancers. This mechanism is important for preventing the uncontrolled growth and survival of cancer cells, slowing tumor progression.
- Limiting Cancer Spread: Fucoidan may inhibit metastasis by preventing cancer cells from adhering to other tissues and by blocking the enzymes that cancer cells use to invade surrounding tissue. Studies suggest it can also reduce angiogenesis, the formation of new blood vessels that supply nutrients to tumors, potentially restricting tumor growth.
- Enhancing Immune Response: Fucoidan may enhance the activity of immune cells, such as natural killer (NK) cells, T-cells, and macrophages, which are essential for recognizing and destroying cancer cells. This immune support can help the body better target and eliminate abnormal cells while bolstering overall resilience.
- Reducing Oxidative Stress: Fucoidan’s antioxidant properties help neutralize free radicals, reducing oxidative damage to cells and DNA, which can lower cancer risk and support healthy cellular function.
- Mitigating Tumor-Related Inflammation: Fucoidan’s anti-inflammatory effects may help reduce inflammatory signals that cancer cells use to grow, slowing cancer development and alleviating some symptoms.
- Protection of Healthy Cells: By supporting immune health and reducing oxidative damage, fucoidan may help protect healthy cells from some of the harmful effects of chemotherapy and radiation.
DOSING: 3 CAPS BID
POSSIBLE SIDE EFFECTS:
- Nausea, Diarrhea, and Stomach Upset: Some individuals report mild digestive discomfort, including nausea, diarrhea, or stomach upset, particularly when taking higher doses of fucoidan.
- Bloating and Gas: High doses may cause bloating or gas, as fucoidan is a high-fiber compound.
- Blood Pressure Lowering Effect: Fucoidan may mildly lower blood pressure, which can benefit those with hypertension but could cause dizziness or lightheadedness in people prone to low blood pressure.
- Blood-Thinning Effects: Fucoidan has mild anticoagulant (blood-thinning) properties, so it may increase bleeding risk, especially for people taking anticoagulants like warfarin or aspirin.
- Iodine Content: Since fucoidan is extracted from seaweed, it may contain iodine, which could affect individuals with thyroid conditions, particularly those sensitive to iodine.
CLASS 3 INHIBITORS
APIGENIN (SWANSON)
BENEFITS:
- Induces Apoptosis in Cancer Cells: Promotes apoptosis (programmed cell death) in various cancer cell lines, including breast, prostate, colon, and skin cancer cells. This helps inhibit tumor growth by targeting cancer cells without affecting normal cells.
- Inhibits Cancer Cell Proliferation: Interferes with cell cycle progression in cancer cells, slowing their growth and spread.
- Reduction of Tumor-Promoting Inflammation: Potent anti-inflammatory effects, reducing the production of pro-inflammatory cytokines, which can help lower cancer risk and inhibit cancer progression.
- Protection Against Oxidative Stress: Powerful antioxidant, neutralizing free radicals and protecting cells from oxidative damage. By reducing oxidative stress, it helps prevent DNA mutations that can lead to cancer and supports healthy cell function.
- Restricts Blood Supply to Tumors: Inhibits angiogenesis (the formation of new blood vessels) around tumors, thereby reducing their nutrient and oxygen supply. This can limit tumor growth and prevent metastasis.
- Protection of Healthy Cells: By reducing oxidative stress and inflammation, apigenin may help protect healthy cells from the harmful effects of chemotherapy and radiation, supporting better treatment tolerance.
- Support for Brain Health: Apigenin has neuroprotective properties, helping reduce inflammation and oxidative damage in brain cells.
- Reduces Blood Pressure and Inflammation: Apigenin may contribute to heart health by reducing blood pressure, lowering cholesterol, and reducing inflammation.
DOSING 50MG: 1 CAP BID
POSSIBLE SIDE EFFECTS:
- Nausea, Diarrhea, and Stomach Upset: Higher doses of apigenin may cause mild digestive discomfort, including nausea, diarrhea, or stomach upset, particularly in sensitive individuals.
- Blood-Thinning Effect: Apigenin may have mild blood-thinning properties, which can increase bleeding risk, especially in individuals taking anticoagulant medications or with bleeding disorders. Consult a healthcare provider if you are on blood-thinning medications.
- Interaction with Certain Drugs: Apigenin can interact with some medications, particularly those metabolized by the liver, by affecting certain enzymes involved in drug metabolism. This may alter the effectiveness or increase the side effects of certain drugs, including blood pressure medications, antidepressants, and sedatives.
- Mild Drowsiness: Apigenin has been observed to have a mild sedative effect, which could lead to drowsiness in some individuals. Avoid driving or operating heavy machinery if you experience drowsiness after taking apigenin supplements.
- Estrogenic Activity: Some studies suggest apigenin may have mild estrogenic effects, so individuals with hormone-sensitive conditions should use it cautiously and consult with a healthcare provider.
CURCUMIN COMPLEX (DFH)
BENEFITS:
- Powerful anti-inflammatory effects by inhibiting inflammatory enzymes and pathways, potentially reducing cancer risk or slowing cancer progression.
- Acts as an antioxidant, neutralizing free radicals that can damage cells and DNA, which are factors in cancer development. By reducing oxidative stress, curcumin may help protect cells from the mutations that lead to cancer.
- Studies have shown that curcumin can inhibit the proliferation of various types of cancer cells, including breast, colon, and prostate cancer. It interferes with cell signaling pathways, slowing or stopping the growth of tumors.
- Promote apoptosis, or programmed cell death, in cancer cells, while having minimal effects on healthy cells.
- Inhibit angiogenesis, potentially slowing or preventing tumor growth.
- Reduce the ability of cancer cells to spread (metastasize) by affecting cellular adhesion, invasion, and migration processes.
- Influence gene expression, potentially "turning off" cancer-promoting genes and "turning on" tumor-suppressor genes, providing another avenue for cancer prevention and treatment.
- Immunomodulatory effects, which can help the immune system recognize and destroy cancer cells more effectively.
DOSING 400MG: 2 CAPS BID
POSSIBLE SIDE EFFECTS:
- May cause mild digestive issues, including nausea, diarrhea, bloating, and acid reflux, especially when taken in large doses.
- High doses of curcumin have been linked to elevated liver enzymes in some individuals, which could indicate liver stress or damage. This is rare and typically occurs with very high doses over extended periods.
- Turmeric (and therefore curcumin) contains oxalates, which may contribute to kidney stone formation in susceptible individuals, especially those with a history of kidney stones or high levels of oxalate in their diet.
- Can interact with various medications, including those metabolized by the liver’s CYP450 enzymes (like certain antidepressants, anti-seizure medications, and chemotherapy drugs). This can impact the effectiveness of these medications or increase their side effects.
- May reduce iron absorption, which could be a concern for
- May lower blood sugar levels, which could be problematic for individuals with hypoglycemia or those taking medication to manage diabetes.
GENISTEIN (VITAL NUTRIENTS)
Genistein, an isoflavone found primarily in soy products, has shown potential in cancer prevention and treatment.
BENEFITS:
- Can act as a weak phytoestrogen, meaning it binds to estrogen receptors in the body. This action may help block the body’s natural estrogen, which can be beneficial for hormone-sensitive cancers like breast and ovarian cancer by reducing estrogen’s growth-stimulating effects on these cancer cells.
- Interferes with several cell signaling pathways, which may inhibit the growth and proliferation of cancer cells. This effect has been observed in various cancers, including breast, prostate, and colon cancer.
- Can trigger apoptosis, or programmed cell death, specifically in cancer cells. This helps prevent cancer cells from accumulating and forming tumors.
- May prevent the formation of new blood vessels (angiogenesis) needed to supply nutrients to tumors, thus slowing tumor growth. This anti-angiogenic property has been studied in cancers such as breast and prostate.
- Antioxidant effects, helping to neutralize free radicals and reduce oxidative stress, which can otherwise lead to DNA damage and increase cancer risk.
- Genistein has been shown to reduce levels of pro-inflammatory molecules, potentially lowering cancer risk and slowing cancer progression.
- Studies suggest that genistein may inhibit the spread (metastasis) of cancer cells to other parts of the body by reducing their ability to migrate and invade other tissues.
- Appears to affect gene expression, potentially “silencing” genes that promote cancer growth and “activating” tumor-suppressor genes.
DOSING: 2 CAPS BID
POSSIBLE SIDE EFFECTS:
- High levels of genistein and other soy isoflavones may interfere with thyroid function by inhibiting thyroid peroxidase, an enzyme critical for thyroid hormone production.
- Some people may experience digestive discomfort, including nausea, bloating, or diarrhea, especially when taking high doses of genistein supplements.
- Estrogen-like effects could potentially affect reproductive hormone balance in both men and women. For example, some studies have suggested that high doses of genistein could impact fertility or alter menstrual cycles in women. In men, there are concerns that high doses might influence testosterone levels and sperm production.
- Some individuals may be allergic to soy products, leading to reactions like itching, swelling, or respiratory issues. This is relevant for genistein supplements derived from soy.
- Can interact with certain medications, including hormone therapies, anticoagulants, and thyroid medications, altering their effectiveness or increasing their side effects. This can be especially important for individuals undergoing hormone therapy or those with thyroid conditions.
- Might lower blood sugar levels, so people with hypoglycemia or those taking medications to control blood sugar should be cautious to avoid hypoglycemia.
INDOL 3 CARBINOL 400 MG (PUR ENCAPSULATIONS/EMERSON)
Indole-3-carbinol (I3C) is a compound found in cruciferous vegetables like broccoli, cabbage, and Brussels sprouts.
BENEFITS:
- I3C is known to support healthy estrogen metabolism, converting estrogen into less active forms that may reduce the risk of hormone-sensitive cancers such as breast, uterine, and prostate cancer. It can lower "bad" estrogen metabolites (16-alpha-hydroxyestrone) while increasing "good" metabolites (2-hydroxyestrone), which are less likely to promote cancer growth.
- I3C enhances the liver’s detoxification enzymes (particularly those in the cytochrome P450 family), which help clear out carcinogens and toxins from the body.
- Studies indicate that I3C can halt the growth and division of cancer cells in several types of cancer, including breast, colon, prostate, and ovarian cancers. It appears to interfere with cell cycle progression, which can prevent cancer cells from replicating.
- I3C promotes apoptosis, or programmed cell death, in cancer cells. This mechanism helps to eliminate abnormal cells, making it more difficult for tumors to grow and spread.
- I3C has been shown to inhibit angiogenesis, the process by which new blood vessels are formed to supply nutrients to growing tumors. This reduction in blood vessel growth can starve tumors, slowing or stopping their progression.
- I3C has anti-inflammatory properties, which may help reduce the levels of inflammation in the body, potentially lowering cancer risk.
- I3C may prevent cancer cells from spreading (metastasis) by inhibiting cellular processes involved in invasion and migration. This effect has been studied in various cancers, including breast and prostate cancer.
- I3C can help protect DNA from oxidative damage, reducing the likelihood of mutations that could lead to cancer development.
DOSING: 1 CAP BID AFTER MEALS
POSSIBLE SIDE EFFECTS:
- I3C supplements may cause digestive issues, including stomach upset, nausea, bloating, and diarrhea. These effects are more common at higher doses.
- I3C affects estrogen metabolism and may influence hormone levels. This could potentially interfere with hormone-sensitive conditions or medications, particularly for individuals with breast, uterine, or prostate cancers. At high doses, I3C may create estrogen metabolites that could theoretically stimulate hormone-sensitive tissues.
- I3C can increase the activity of liver enzymes involved in detoxification, which may interfere with medications metabolized by the liver. This enzyme induction could lower the effectiveness of certain medications or cause them to be cleared from the body more quickly.
- Some individuals may develop a mild skin rash when taking I3C supplements. This is typically rare and tends to resolve when the dose is reduced or discontinued.
- In some cases, I3C can cause mild headaches or dizziness, particularly if taken at higher doses.
- I3C and other compounds found in cruciferous vegetables may affect thyroid function, particularly in people with an iodine deficiency. Although the risk is minimal when eating whole vegetables, high-dose supplements could potentially interfere with thyroid hormone production.
- I3C may interact with various medications, including anticoagulants, hormone replacement therapy, and medications metabolized by the liver’s cytochrome P450 enzymes. It’s advisable to check for potential interactions, especially if taking medications for blood pressure, hormones, or cancer.
- At high doses, I3C may have pro-oxidant effects, which could potentially lead to oxidative stress and damage cells instead of protecting them. This effect is not typically seen at dietary levels but may occur with high-dose supplementation.
PAW PAW (NATURES SUNSHINE PRODUCT)
Paw paw (Asimina triloba), particularly its extract from the bark, twigs, and seeds.
https://shop.naturessunshine.com/product/paw-paw
BENEFITS:
- Acetogenins found in paw paw can block the production of ATP (adenosine triphosphate) in cancer cells. ATP is the primary energy source for cells, and without it, cancer cells struggle to survive and grow. This action makes paw paw particularly interesting for targeting cells with high energy demands, such as cancer cells.
- The unique mechanism of acetogenins enables them to selectively target cancer cells with high metabolic rates without significantly affecting normal cells. Cancer cells often have more active ATP-producing mitochondria than normal cells, making them more susceptible to the effects of paw paw.
- By disrupting energy production and interfering with essential cellular processes, paw paw may prevent cancer cells from dividing and multiplying. This anti-proliferative effect has been studied in various types of cancer, including breast, lung, prostate, and colon cancers.
- Appears to promote apoptosis in cancer cells. By triggering this natural process, paw paw helps eliminate abnormal cells that would otherwise contribute to tumor growth.
- Some studies suggest that paw paw may prevent the spread (metastasis) of cancer cells by interfering with their ability to migrate to other tissues.
- Cancer cells can develop resistance to multiple chemotherapy drugs, a process often mediated by P-glycoprotein pumps that expel drugs from the cells. Acetogenins in paw paw may inhibit these pumps, making chemotherapy drugs more effective in resistant cancer cells.
DOSING: 2 CAPS TID with food
POSSIBLE SIDE EFFECTS:
- May cause digestive upset, including nausea, vomiting, and diarrhea. These effects are more likely at higher doses.
- Some studies have shown that paw paw may be neurotoxic, potentially causing nerve damage with long-term use. Symptoms may include tremors or numbness. This risk is due to certain compounds in paw paw that may affect the central nervous system, so it’s generally not recommended for people with existing neurological conditions.
- Can cause a drop in blood pressure. While this may benefit individuals with hypertension, it could lead to hypotension (abnormally low blood pressure) in others, causing dizziness, lightheadedness, or fainting.
- At high doses, paw paw may cause liver stress or toxicity.
- Since paw paw works by disrupting ATP production in cells, it can affect not only cancer cells but also healthy cells, especially if taken in large amounts. This can lead to fatigue, muscle weakness, and other symptoms related to reduced cellular energy.
- May interfere with certain medications, particularly those metabolized by the liver. It may also enhance the effects of sedatives or blood pressure medications, leading to increased side effects.
- Paw paw has been reported to suppress appetite in some users, which could lead to unintended weight loss.
QUERCETIN (CMP)
Quercetin is a powerful antioxidant, helping to neutralize free radicals that can damage cells and DNA
BENEFITS:
- Reduces inflammation by inhibiting inflammatory enzymes and cytokines, potentially lowering the risk of cancers linked to chronic inflammation, such as colon and liver cancer.
- Studies have shown that quercetin can inhibit the growth and division of cancer cells. It does this by blocking certain signaling pathways and cell cycle progression, making it harder for cancer cells to multiply. This effect has been observed in various cancers, including breast, colon, prostate, and lung cancers.
- Can trigger apoptosis, or programmed cell death, in cancer cells while sparing normal cells.
- May prevent the formation of new blood vessels (angiogenesis) that tumors need to grow and spread. This anti-angiogenic effect helps “starve” tumors, making it difficult for them to obtain the nutrients they need to expand.
- May help prevent cancer cells from spreading to other parts of the body by inhibiting cellular processes involved in migration and invasion.
- Can influence gene expression, potentially turning off cancer-promoting genes and activating tumor-suppressor genes.
- Immune-modulating effects, helping to boost the body’s ability to recognize and destroy cancer cells.
DOSING: 1000MG TID (CMP) for C3, 500MG BID FOR ONGOING SUPPORT
POSSIBLE SIDE EFFECTS:
- High doses of quercetin can cause digestive discomfort, including nausea, stomach upset, bloating, and diarrhea. These effects are more common with large doses taken on an empty stomach.
- Some people may experience mild headaches when taking quercetin supplements, especially at higher doses. This side effect is typically mild and may go away with dose adjustment.
- Large doses of quercetin have been associated with tingling or numbness in the extremities in some cases.
- Can interact with certain medications, particularly those metabolized by the liver’s cytochrome P450 enzymes, such as blood thinners, certain antibiotics, and chemotherapy drugs. It may either increase or decrease the effectiveness of these drugs.
- Has mild blood pressure-lowering effects, which may benefit those with hypertension but could lead to low blood pressure (hypotension) in others.
Some studies have indicated that high doses of quercetin might interfere with thyroid function, potentially inhibiting thyroid hormone production.
RESVERATROL (CMP)- DO NOT USE WITH HORMONE POSITIVE CANCERS
Resveratrol, a polyphenol found in foods like grapes, berries, and red wine
BENEFITS:
- Powerful antioxidant that helps neutralize free radicals, which can damage cells and DNA. By reducing oxidative stress, resveratrol may lower the risk of mutations that lead to cancer.
- Has strong anti-inflammatory properties, inhibiting inflammatory enzymes and cytokines that drive cancer-promoting inflammation, which can be especially beneficial in cancers associated with chronic inflammation, like colorectal cancer.
- Studies have shown that resveratrol can inhibit the proliferation of various cancer cells, including breast, prostate, colon, and lung cancer cells. It interferes with cell cycle progression, making it harder for cancer cells to multiply.
- Triggers apoptosis, or programmed cell death, in cancer cells. This helps to eliminate abnormal cells that would otherwise contribute to tumor growth while sparing healthy cells.
- Can inhibit this process, potentially "starving" tumors and slowing their growth and progression.
- Has been shown to reduce cancer cell migration and invasion, thus helping to prevent metastasis (the spread of cancer to other parts of the body).
- Can influence gene expression by modulating epigenetic processes. It may turn on tumor-suppressor genes and inhibit cancer-promoting genes, providing a potential layer of cancer prevention and control.
- Immune-modulating effects, helping to strengthen the body’s ability to recognize and destroy cancer cells.
DOSING: 300MG TID (CMP)- DO NOT USE FOR HORMONE RECEPTIVE CANCERS
POSSIBLE SIDE EFFECTS:
- High doses of resveratrol may cause digestive issues, including nausea, diarrhea, and stomach cramps. Taking resveratrol with food may help reduce these effects.
- Has mild blood-thinning properties, which could increase bleeding risk, especially for those taking anticoagulant or antiplatelet medications (e.g., warfarin, aspirin) or those with bleeding disorders.
- Can interact with certain medications, particularly those metabolized by the liver’s cytochrome P450 enzymes, including statins, NSAIDs, and some antidepressants. This interaction may affect the drug's effectiveness or increase side effects.
- Has mild estrogenic activity, which could potentially impact hormone-sensitive conditions like breast, ovarian, or uterine cancers, as well as endometriosis.
- Has been reported to lower blood pressure slightly
- May inhibit the absorption of iron, so individuals with iron deficiency or anemia should monitor their iron levels if using high doses over time.
SEA CUCUMBER
Swanson
BENEFITS:
- Inhibition of Angiogenesis: Angiostop contains compounds that may block the development of new blood vessels, thereby starving tumors of essential nutrients and oxygen needed for their growth.
- Induction of Apoptosis: Promote apoptosis (programmed cell death) in cancer cells, aiding in the reduction of tumor size and preventing further proliferation.
- Aromatase Inhibition: Natural aromatase inhibitor, which can be beneficial in managing estrogen-dominant cancers by reducing estrogen levels that may fuel certain types of tumors.
DOSING: 1 CAPS BID AFTER MEALS
POSSIBLE SIDE EFFECTS:
- Nausea, Stomach Upset, and Diarrhea: Some people may experience mild digestive discomfort, including nausea, stomach upset, or diarrhea, particularly when starting Angiostop or taking it at higher doses.
- Anticoagulant Effects: Sea cucumber extract has mild blood-thinning properties, so Angiostop may increase bleeding risk, especially for those taking anticoagulants like warfarin or aspirin.
- Potential Hormonal Interactions: As Angiostop may act as a natural aromatase inhibitor, it could potentially interact with hormonal medications or affect hormone-sensitive conditions.
VACUSTATIN (ALLERGY RESEARCH/EMERSON)
VascuStatin is a dietary supplement derived from the plant Convolvulus arvensis, commonly known as field bindweed. It contains a proteoglycan mixture (PGM) that has been studied for its potential anti-angiogenic properties, meaning it may inhibit the formation of new blood vessels that tumors require for growth and metastasis.
BENEFITS:
- The PGM in VascuStatin has demonstrated the ability to inhibit new blood vessel formation, which is crucial for tumor development and spread. In laboratory studies, PGM inhibited new blood vessel growth by up to 73% in a dose-dependent manner.
- Animal studies have shown that PGM can significantly reduce tumor growth. For instance, in mouse models with fibrosarcoma and lung carcinoma, PGM administration resulted in tumor growth inhibition ranging from 54% to 77%, depending on the dosage.
- PGM has been observed to stimulate the immune system by inducing lymphocyte growth and enhancing phagocytic activity, potentially aiding the body's natural defenses against cancer cells.
DOSING 2GMS: 4 CAPS BID
POSSIBLE SIDE EFFECTS:
- Some users report mild digestive issues, including nausea, stomach cramps, and diarrhea. Taking VascuStatin with food may help reduce these effects.
- Since VascuStatin has anti-angiogenic properties, it could interfere with normal blood vessel formation needed for wound healing. Individuals recovering from surgery or injuries should be cautious with VascuStatin, as it may delay healing.
- Thought to stimulate certain immune activities, which could potentially lead to overstimulation in individuals with autoimmune conditions.
- May cause a mild reduction in blood pressure, which could lead to dizziness or lightheadedness in susceptible individuals, especially those who already have low blood pressure or are on antihypertensive medications.
- Due to its anti-angiogenic effects, VascuStatin may not be appropriate for individuals with certain heart or vascular conditions, as these patients may benefit from angiogenesis to support blood flow in the heart and peripheral tissues.
- May interact with medications that affect blood clotting (anticoagulants or antiplatelets), blood pressure medications, or immune-modulating drugs.
Natural Substances that DO NOT work well together
- Genistein – Do not mix with Quercetin during the same month
- Vascustatin – Do not mix with Genistein during the same month
- Artecin – Do not use with Super Artemisinin during the same month
- Poly MVA – Do not mix with Lycopene on the same day
- IV – C – Do on opposite days of PolyMVA - or at least 6-8 hours after IV
- Salvestrol – Do not take with Resveratrol during the same month
- Artecin or Super Artemisinin - Do not do oral vitamin C on the same days
- No ECGC on Days of IV Vit C
- Do not use C-Statin and Vacustatin in the same month
DAILY CANCER SUPPORT
- MELATONIN QHS|START 20MG AND TITRATE TO 60MG (CMP)-downregulate genes
- FINASTERIDE 1MG DAILY (COMM) block DHT
- LDN 4.5MG DAILY (CMP)- anti-inflammation
- BPC-157 1 CAP DAILY (CMP)- gut health
- METHYLENE BLUE 16MG DAILY (CMP)- mitochondria support- ALTERNATE MONTHS
- FREESTYLE LIBRE FOR TIGHT GLUCOSE CONTROL (CMP)- monitor blood sugars (1 unit- 14 day supply)
- EGCG 225MG (DFH) 1 CAP BID- downregulate genes (1 bottle-30 day supply)
- ROSEMARY 700MG (NATURES WAY/EMERSON) 2 CAPS BID-downregulate genes (1 bottle-25 day supply)
- OMEGA (EPA 575MG/DPA 425MG) (INWELL) 1 CAP TID-downregulate genes (2 bottles-45 day supply)
- ACETYL-L-CARNITINE 800MG (DFH) 1 CAP BID-downregulate genes (1 bottle-45 day supply)
- QUERCETIN 500MG BID (CMP)-downregulate genes
- PROBIOTIC 25+ (INWELL) 1 CAP QD-Foundational (microbiome)(1 bottle-60 day supply)
- STUDIO D3K2 4 DROPS QD-downregulate genes (1 bottle-45 day supply)
- DASATINIB/QUERCETIN 500/50MG BID 3 DAYS MONTHLY (CMP)- remove zombie cells (anti-inflammation)
- RAPAMYCIN ONCE WEEKLY (CMP)- downregulate mTOR